A novel subunit vaccine based on Fiber1/2 knob domain provides full protection against fowl adenovirus serotype 4 and induces stronger immune responses than a Fiber2 subunit vaccine

ABSTRACT: Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry in China since 2015.However, commercially available vaccines against the FAdV-4 infection remain scarce.In our study, subunit vaccine candidates derived from the bacterially exp

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Preterm birth and its associated factors among reproductive aged women in sub-Saharan Africa: evidence from the recent demographic and health surveys of sub-Sharan African countries

Abstract Background Globally, preterm birth is the leading cause of neonatal and under-five children mortality.Sub-Saharan African (SSA) accounts for the majority of preterm birth and death following its complications.Despite this, there is limited evidence about the pooled prevalence and associated factors of preterm birth at SSA level using natio

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Hypoglycemic Effects in Alloxan-Induced Diabetic Rats of the Phenolic Extract from Mongolian Oak Cups Enriched in Ellagic Acid, Kaempferol and Their Derivatives

Our previous reports showed that crude extract prepared with 50% ethanol (ethanol crude extract, ECE) from Mongolian oak cups possessed excellent in vitro antioxidant capacities as well as inhibitory activities against α-glucosidase, α-amylase and protein glycation caused by its enrichment in phenolics, including mainly ellagic acid, ka

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